Human Disease Pedigree Analysis Report

Subject area Biology Subject area Biology
You are expected to prepare a human pedigree detailing the inheritance of a single genetic disease or disorder. The pedigree must contain at least five generations and include examples of all of the symbols associated with pedigree analysis, including living and deceased familial members, disease trait carriers vs. fully afflicted individuals, and male vs. female members. The pedigree must show at least two marriage events, and each familial generation must be labeled as is customary for authentic human pedigrees. After depicting the disease on the pedigree, you should include in your brief summary a brief (two- to three-sentence) explanation of the disorder, its dominant or recessive inheritance pattern, and its autosomal or sex-linked position in the human genome. Also, you should include a brief description of the manifestations and clinical outcomes of the disease. You should prepare this assignment in Word so it can be uploaded to the Assignments folder by the date indicated in the syllabus. This assignment is worth 100 points (25 points for the five-generation pedigree; 25 points for the correct use of pedigree annotation and labeling; 25 points for appropriate depictions of the inherited disease or disorder on the pedigree; and 25 points for the write-up at the bottom of the pedigree, detailing dominant vs. recessive and autosomal vs. sex-linked inheritance patterns).